Serum Level Changes of Neurotrophin-3 after Performing Diabetic Foot Exercise in Diabetic Neuropathy
Tri Wahyuliati, Agung Pranoto, Samekto Wibowo
Abstract
The research aimed to determine the pattern of changes in serum levels of NT-3 in the improvement of diabetic neuropathy, after doing diabetic foot exercise. A true experimental study with randomaized pre – post test control trial. A total of 36 subjects meeting the inclusion and exclusion criteria were included in the exercise group or the control one with age matched systematic random sampling method. Exercise group had a significant improvement on the score of ABI (p .0.002), systolic blood pressure (p .0.014), diastolic blood pressure (p .0.055), DNS (p .0.01), DNE (p .0.001) and increased of serum level of NT-3 (p .0.049). Control group had result respectively on ABI (p .0.131), systolic blood pressure (p .0.668), diastolic blood pressure (p .0.216), DNS (p .1.00), DNE (p .0.543), and increase of NT-3 (p .0.264). The comparation results of the two groups had a significant different on the score of ABI (p .0.01), systolic blood pressure (p .0.01), diastolic blood pressure (p .0.01), DNS (p .0.01), DNE (p .0.01), and increased of NT-3 (p .0.01). Diabetic foot exercise had a peripheral affect on a clinically significant improvement based on ABI scores, systolic and diastolic blood pressure, DNS and DNE, and increase of serum level of NT-3.
DOI:
http://doi.org/10.11591/ijphs.v4i4.4750
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International Journal of Public Health Science (IJPHS) p-ISSN: 2252-8806, e-ISSN: 2620-4126
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